Columbus Nanoworks, Inc., is a
nanotechnology company specializing in custom biomolecule-coated paramagnetic nanoparticles. Formed in 2004 by principals
Dr. Arfaan Rampersaud and Kristie Melnik, Columbus Nanoworks is the
remarkable success story of two highly talented Ohio scientists.
Dr. Arfaan Rampersaud
is an Ohio native and received a BS degree in Chemistry from Defiance
College and a PhD degree in Biochemistry from Kent State University.
After working as a scientist for several years in The Ohio State
University Department of Pathology, he worked for two Ohio biotech companies, Athersys and
Kristie Melnik received her BS degree in
Microbiology. She worked in The Ohio State University Department of
Pathology, then later in the Department of Chemical Engineering for
several years. In the Department of Pathology, she used magnetic
particles to separate stem cells from contaminant cells in cord blood
banking and bone marrow transplants. Following this work, she went to
Battelle and then to IMEDD, where she met Dr. Rampersaud.
Between 2004 and 2008, Dr.
Rampersaud and Ms. Melnik authored and won four winning SBIR and STTR
grants. Columbus Nanoworks began in July 2004 with ten square feet of
rented space at The Ohio State University's Nanotech West Laboratory
on Kinnear Road on the West Campus of the University. The company has
grown continually since that time and now occupies new office and lab
space on Chambers Road, while still utilizing equipment at Nanotech
Columbus Nanoworks is the first
company of its kind to be able to produce and market biomacromolecule-coated nanoparticles from beginning to end. Using proprietary
processes, it is able to produce paramagnetic nanoparticles, coat them
with dextran for solubility in aqueous systems, and attach
macromolecule ligands such as antibodies or fluorochromes to
functional groups on the dextran coatings. Testing is currently
underway to evaluate the capability of these particles to identify
cancer and stem cells in various systems.
Columbus Nanoworks, Inc.
1507 Chambers Road
Columbus, OH 43064